Connectomics has enhanced our understanding of neurocognitive development and decline by the integration of network sciences into studies across different stages of the human life span. To pursue the opportunity to test integrated models of the dynamical brain organization across the entire life span, we target a national lifespan cohort on development of human brain and mind. With the success of building up this cohort, we will develop a novel computational and neuroinformatic platform for achieving a set of normative trajectories of the human brain and its mind/behavior associations. As initial findings, we have observed that across the life span, the human connectome gradually shifts from an ‘anatomically driven’ organization to one that is more ‘topological’. The whole framework, namely C3, can be systematically divided into to three parts, which accounts for cohort design, reproducibility assurance and methodology, respectively.
Methodology – Connectome Computation
Reproducibility and Reliability – CoRR
Cohort – Chinese Color Nest Project